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Preclinical data reveal no special hazard for humans based on conventional studies of general pharmacologyrepeated dose toxicitygenotoxicityand carcinogenic potentialAngiotensin-converting enzyme inhibitorsas a classhave been shown to induce adverse effects on the late foetal developmentresulting in foetal death and congenital effectsin particular affecting the skullFoetotoxicityintrauterine growth retardation and patent ductus arteriosus have also been reportedThese developmental anomalies are thought to be partly due to a direct action of ACE inhibitors on the foetal renin-angiotensin system and partly due to ischaemia resulting from maternal hypotension and decreases in foetal-placental blood flow and oxygen/nutrients delivery to the foetus.

Take Zestril exactly as prescribed by your doctorFollow all directions on your prescription labelYour doctor may occasionally change your dose to make sure you get the best resultsDo not take this medicine in larger or smaller amounts or for longer than recommended.

Lisinopril may rarely cause seriouspossibly fatalliver problemsGet medical help right away if you have any symptoms of liver damagesuch asnausea/vomiting that doesn’t stoploss my pharmacy 365. of appetitestomach/abdominal painyellowing eyes/skindark urine.

To reduce signs/symptoms of systolic heart failureAdjunct to other therapies within 24hrs post-MI in hemodynamically stable patientsto reduce mortality.

To treat high blood pressurehypertensionTo treat heart failureIf you have recently had a heart attackmyocardial infarctionTo treat kidney problems caused by Type II diabetes in people with high blood pressure.

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