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Acetaminophen; guaifenesin; phenylephrine major agents which induce the hepatic isoenzyme cyp2e1, such as isoniazid, may potentially increase the risk for acetaminophen-induced hepatotoxicity via generation of a greater percentage of acetaminophen s hepatotoxic metabolites.

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Your doctor should order liver function tests while you are taking this medicationKeep all medical and laboratory appointments.

Serum concentrations of hepatic transaminases should be monitored whenever possible.

Drugs other than those listed here may also interact with isoniazidTalk to your doctor and pharmacist before taking any prescription or over-the-counter medicinesincluding vitaminsmineralsand herbal products.

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