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In harmonising the contraindicationsthe CHMP decided against including two contraindications that were in the SmPCs of some EU countriesliver impairment and pre-operative use in patients whose receptor status is negative or unknownThe CHMP was of the view that it was more appropriate to include relevant warnings in section 4.4.
Letrozole can cause an increase in your cholesterol levelsYour healthcare team will monitor your cholesterol levels throughout you treatment.
Letrozole can cause an increase in your cholesterol levelsYour healthcare team will monitor your cholesterol levels throughout you treatment.
The blood levels of this medication can be affected by certain foods and medicationsso they should be avoidedBe sure to tell your healthcare provider about all medications and supplements you takeYou should not take this medication if you are currently taking tamoxifenor other medications that include estrogenincluding hormone replacement therapybirth control pillsestrogen creamsvaginal ring and vaginal suppositories.
FEMARA tablets is indicated for first-line treatment of postmenopausal women with hormone receptor-positive or unknownlocally advancedor metastatic breast cancerFEMARA is also indicated for the treatment of advanced breast cancer in postmenopausal women with disease progression following antiestrogen therapy.
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