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Also, colchicine was awarded orphan drug exclusivity for 7 years, not 3 years as originally stated.

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If you are taking this medication to prevent attacks of pain caused by familial Mediterranean feverthe usual dose is 1.2 to 2.4 milligrams dailyThe total dose may be taken once daily or divided into two doses a dayYour doctor may need to adjust your dose to control your symptoms or if you have side effects.

Colchicine may cause severe bone marrow depressionagranulocytosisaplastic anaemiathrombocytopeniaThe change in blood counts may be gradual or very suddenAplastic anaemia in particular has a high mortality ratePeriodic checks of the blood picture are essential.

Advise patients that bone marrow depression with agranulocytosisaplastic anemiaand thrombocytopenia may occur with colchicine capsules.

Colchicine capsules are not an analgesic medication and should not be used to treat pain from other causes.

This medication is used to prevent or treat gout attacksflaresUsually gout symptoms develop suddenly and involve only one or a few jointsThe big toekneeor ankle joints are most often affectedGout is caused by too much uric acid in the bloodWhen uric acid levels in the blood are too highthe uric acid may form hard crystals in your jointsColchicine works by decreasing swelling and lessening the build up of uric acid crystals that cause pain in the affected joint(s

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