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Azathioprine wikipedia azathioprine aza , sold under the brand name imuran among others, is an immunosuppressive medication.

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Information is available on the risk of malignancy with the use of IMURAN in rheumatoid arthritissee ADVERSE REACTIONSIt has not been possible to define the precise risk of malignancy due to IMURANThe data suggest the risk may be elevated in patients with rheumatoid arthritisthough lower than for renal transplant patientsHoweveracute myelogenous leukemia as well as solid tumors have been reported in patients with rheumatoid arthritis who have received IMURAN.

The dose of IMURAN required to prevent rejection and minimize toxicity will vary with individual patientsthis necessitates careful managementThe initial dose is usually 3 to 5 mg/kg dailybeginning at the time of transplantIMURAN is usually given as a single daily dose on the day ofand in a minority of cases 1 to 3 days beforetransplantationDose reduction to maintenance levels of 1 to 3 mg/kg daily is usually possibleThe dose of IMURAN should not be increased to toxic levels because of threatened rejectionDiscontinuation may be necessary for severe hematologic or other toxicityeven if rejection of the homograft may be a consequence of drug withdrawal.

IMURAN should not be given to patients who have shown hypersensitivity to the drugIMURAN should not be used for treating rheumatoid arthritis in pregnant womenPatients with rheumatoid arthritis previously treated with alkylating agentscyclophosphamidechlorambucilmelphalanor othersmay have a prohibitive risk of malignancy if treated how long paroxetine take to work. with IMURAN.

It is used to keep the body from turning down the kidney after a kidney transplantIt is used to treat rheumatoid arthritisIt may be given to you for other reasonsTalk with the doctor.

If you have an allergy to azathioprine or any other part of Imuranazathioprine tabletsIf you are allergic to any drugs like this oneany other drugsfoodsor other substancesTell your doctor about the allergy and what signs you hadlike rashhivesitchingshortness of breathwheezingcoughswelling of facelipstongueor throator any other signsIf you have ever been treated with chlorambucilcyclosporineor melphalan in the pastIf you are breast-feeding or plan to breast-feed.

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