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The combination of ZETIA with a statin is contraindicated in patients with active liver disease or unexplained persistent elevations in hepatic transaminase levelsWomen who are pregnant or may become pregnantBecause statins decrease cholesterol synthesis and possibly the synthesis of other biologically active substances derived from cholesterolZETIA in combination with a statin may cause fetal harm when administered to pregnant womenAdditionallythere is no apparent benefit to therapy during pregnancyand safety in pregnant women has not been establishedIf the patient becomes pregnant while taking this drugthe patient should be apprised of the potential hazard to the fetus and the lack of known clinical benefit with continued use during pregnancySee Use in Specific PopulationsNursing mothersBecause statins may pass into breast milkand because statins have the potential to cause serious adverse reactions in nursing infantswomen who require ZETIA treatment in combination with a statin should be advised not to nurse their infantssee Use in Specific PopulationsPatients with a known hypersensitivity to any component of this productHypersensitivity reactions including anaphylaxisangioedemarash and urticaria have been reported with ZETIAsee ADVERSE REACTIONS

Clinical adverse events occurring in2of patients treated with ezetimibe and at an incidence greater than placeboregardless of causality

NoteThis document contains side effect information about ezetimibeSome of the dosage forms listed on this page may not apply to the brand name Zetia.

Ever had liver problemsZETIA may not be right for youare pregnant or plan to become pregnantYour doctor will discuss with you whether ZETIA is right for youare breastfeedingWe do not know if ZETIA can pass to your baby through your milkYour doctor will discuss with you whether ZETIA is right for youexperience unexplained muscle paintendernessor weakness.

Take with or without foodTake Zetiaezetimibeat the same time of dayTo gain the most benefitdo not miss dosesKeep taking Zetiaezetimibeas you have been told by your doctor or other health care providereven if you feel well.

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less serious side effects of zetia include tiredness headache dizziness numbness and tingling stomach ache, diarrhea depressed moods cough cold symptoms allergic reaction, hives, difficulty breathing gallstones.

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