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Hepaticmainly via CYP3A4Tinidazolelike metronidazoleis significantly metabolized in humans prior to excretionTinidazole is partly metabolized by oxidationhydroxylation and conjugationTinidazole is the major drug-related constituent in plasma after human treatmentalong with a small amount of the 2-hydroxymethyl metabolite.

Every effort has been made to ensure that the information provided by Cerner MultumIncMultumis accurateup-to-dateand completebut no guarantee is made to that effectDrug information contained herein may be time sensitiveMultum information has been compiled for use by healthcare practitioners and consumers in the United States and therefore Multum does not warrant that uses outside of the United States are appropriateunless specifically indicated otherwiseMultum’s drug information does not endorse drugsdiagnose patients or recommend therapyMultum’s drug information is an informational resource designed to assist licensed healthcare practitioners in caring for their patients and/or to serve consumers viewing this service as a supplement toand not a substitute forthe expertiseskillknowledge and judgment of healthcare practitionersThe absence of a warning for a given drug or drug combination in no way should be construed to indicate that the drug or drug combination is safeeffective or appropriate for any given patientMultum does not assume any responsibility for any aspect of healthcare administered with the aid of information Multum providesThe information contained herein is not intended to cover all possible usesdirectionsprecautionswarningsdrug interactionsallergic reactionsor adverse effectsIf you have questions about the drugs you are takingcheck with your doctornurse or pharmacist.

This medication may cause your urine to turn darker in colorThis effect is harmless and will disappear when the medication is stopped.

FDA pregnancy category CDo not take tinidazole during the first 3 months of pregnancyTell your doctor if you are pregnant or plan to become pregnant during treatment.

Avoid alcoholic beverages and products containing propylene glycol while taking this medication and for at least 3 days after finishing this medicine because severe stomach upset/crampsnauseavomitingheadacheand flushing may occur.

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tinidazole is excreted in the urine mainly as unchanged drug approximately 20-25 of the administered dose .

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