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Increased side effects from other drugsTaking methotrexate with certain medications raises your risk of side effects from those drugsExamples of these drugs include:

Do not use methotrexate to treat psoriasis or rheumatoid arthritis if you have low blood cell countsa bone marrow disorderliver diseaseespecially if caused by alcoholismor if you are pregnant or breast-feeding.

Examples of drugs that can cause interactions with methotrexate are listed below.

Methotrexate is usually not taken every dayYou must use the correct dose for your conditionSome people have died after taking methotrexate every day by accident.

Methotrexate self-injectable solution may be used as part of a combination therapyThat means you may need to take it with other drugs.

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your doctor may tell you that you should not take methotrexate unless you have life-threatening cancer.

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