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Indeed, a high degree of cross resistance with other protease inhibitors has been demonstrated in indinavir-resistant clinical isolates of hiv selected during indinavir therapy.

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Maintaining a normal weighteating a healthy dietexercising regularlyand quitting smoking are all important in helping you to reduce your risk of diabetesheart diseaseand other complicationsRegular visits to your doctor for checkups and blood tests are a vital part of staying healthyIf necessaryyour doctor can prescribe lipid-lowering therapy.

Concomitant use of CRIXIVAN and StJohn’s wortHypericum perforatumor products containing StJohn’s wort is not recommendedCoadministration of CRIXIVAN and StJohn’s wort has been shown to substantially decrease indinavir concentrationssee CLINICAL PHARMACOLOGYDRUG INTERACTIONSand may lead to loss of virologic response and possible resistance to CRIXIVAN or to the class of protease inhibitors.

Indinavir is a type of anti-HIV drug called a protease inhibitorThe most common side effects of indinavir can include nauseaheadachediarrheavomitingand weaknessIndinavir can also cause kidney stonesbut drinking a minimum of 1.5 litres of water dailyin addition to your regular intake of other fluidscan help reduce this complication.

Some drugs can interact with indinavirincreasing or decreasing its levels in your bodyIncreased drug levels can cause you to experience side effects or make pre-existing side effects worseOn the other handif drug levels become too lowHIV can develop resistance and your future treatment options may be reduced.

Particular caution should be used when prescribing sildenafiltadalafilor vardenafil in patients receiving indinavirCoadministration of CRIXIVAN with these medications is expected to substantially increase plasma concentrations of sildenafiltadalafiland vardenafil and may result in an increase in adverse eventsincluding hypotensionvisual changesand priapismwhich have been associated with sildenafiltadalafiland vardenafilsee CONTRAINDICATIONS and PRECAUTIONSDRUG INTERACTIONS and PATIENT INFORMATIONand the manufacturer’s complete prescribing information for sildenafiltadalafilor vardenafil

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