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Ethionamide may also be used for purposes not listed in this medication guide.

For the best effecttake this antibiotic at evenly spaced timesTo help you remembertake this medication at the same time(severy day.

Ethionamide may be bacteriostatic or bactericidal in actiondepending on the concentration of the drug attained at the site of infection and the susceptibility of the infecting organismEthionamidelike prothionamide and pyrazinamideis a nicotinic acid derivative related to isoniazidIt is thought that ethionamide undergoes intracellular modification and acts in a similar fashion to isoniazidIsoniazid inhibits the synthesis of mycoloic acidsan essential component of the bacterial cell wallSpecifically isoniazid inhibits InhAthe enoyl reductase from Mycobacterium tuberculosisby forming a covalent adduct with the NAD cofactorIt is the INH-NAD adduct that acts as a slowtight-binding competitive inhibitor of InhA.

NOTESDo not share this medication with others.Laboratory and/or medical testssuch as sputum testeye/vision examsliver/thyroid functionblood glucosecomplete blood countshould be performed periodically to monitor your progress or check for side effectsConsult your doctor for more details.

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