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The prescriber should be aware that these figures cannot be used to predict the incidence of adverse events in the course of usual medical practice where patient characteristics and other factors differ from those which prevailed in the clinical trialsSimilarlythe cited frequencies cannot be compared with figures obtained from other clinical investigations involving different treatmentsusesand investigatorsThe cited figureshoweverdo provide the prescribing physician with some basis for estimating the relative contribution of drug and non-drug factors to the adverse event incidence rate in the population studied.
Talking therapysuch as cognitive behavioural therapyexercise programmes help to get a good night’s sleep.
Don’t expect to feel better overnightthoughSome people feel worse during the first few weeks of treatment before they begin to feel better.
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