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Begin therapy 1 week before target quit dateusually second week of treatmentMay be combined with the use of the nicotine patch.

If you take Zyban to help you stop smokingyou may continue to smoke for about 1 week after you start the medicineSet a date to quit smoking during the second week of treatmentTalk to your doctor if you are having trouble quitting after you have used Zyban for at least 7 weeks.

Assess blood pressure before initiating treatment with sustained release formulationand monitor periodically during treatmentrisk of hypertension is increased if sustained release formulation is used concomitantly with MAOIs or other drugs that increase dopaminergic or noradrenergic activityuse caution in people with cardiovascular disease.

Neuropsychiatric adverse events reported in patients without and with pre-existing psychiatric diseasesome patients experienced worsening of their psychiatric illnessesobserve patients for occurrence of neuropsychiatric adverse eventspatient should stop therapy and contact healthcare provider immediately if agitationdepressed moodor changes in behavior or thinking that are not typical for patient are observedor if patient develops suicidal ideation or suicidal behaviorsymptoms may persist after discontinuation of therapyin some casesmonitoring and supportive care should be provided until symptoms resolve.

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