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ADrugs can cause weight gain in several different waysSome can increase appetite or make you crave certain types of foods like those high in carbohydrates or fatOther medications may slow down metabolism or cause fluid retentionHoweverthe effect of prescription drugs on body weight is complexSome drugs have no effect on weightwhile others cause weight gain or weight lossAlsothe same medications can cause weight gain in certain individuals and weight loss in othersThere are also drugs that initially cause weight loss and then lead to weight gain with long-term useMost prescription medications associated with changes in body weight affect the central nervous systemThese include antidepressants like monoamine oxidase inhibitorsMAOIstricyclic antidepressantsand selective serotonin reuptake inhibitorsSSRIsMood stabilizerslithiumvalproic acidantipsychoticsand anticonvulsants have also been linked with weight gainOther drugs that have been reported to cause weight gain include diabetes medicationsinsulinsulfonylureasand thiazolidinedionesantihypertensive drugscertain hormonal contraceptivescorticosteroidsantihistaminessome chemotherapy regimensand antiretroviral protease inhibitorsBenadryldiphenhydramineis an antihistaminemeaning that it blocks the effects of the naturally occurring chemical histamine in the bodyBenadryl is used to treat sneezingrunny noseitchingwatery eyeshivesrashesitchingand other symptoms of allergies and the common coldIt can also be used to treat motion sicknessinsomniaand mild forms of Parkinson’s diseaseCommon side effects of Benadryl includes sleepinessfatiguedizzinessheadachedry mouthand difficulty urinatingThis is not a complete list of side effects that can occur with BenadrylBenadryl can cause side effects that impair your thinking and reactionsso use caution when doing anything that requires alertnessImpaired thinking can be more common in elderly patientsover the age of 70and at higher dosesContact your doctor if you are experiencing memory problems or memory lossA search of the manufacturer’s product information and a drug database did not specifically list weight gain as a side effect of BenadrylIf you think a drug you are taking is causing weight gaintell your health care providerDo not stop any medication or change the dose without first talking to your providerFor more specific informationconsult with your doctor or local pharmacist for guidance based on your health status and current medicationsSarah LewisRPh.

An overdose of Benadryl may cause symptoms that include excitabilityblurred visionseizureconfusioninability to pass urineand loss of consciousnessand these may be especially dangerous for young children.

By Chris IliadesMDMedically Reviewed by Pat FBass IIIMDMPH.

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