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Raloxifene appears to act as an estrogen agonist in boneIt decreases bone resorption and bone turnoverincreases bone mineral densityBMDand decreases fracture incidencePreclinical data demonstrate that raloxifene is an estrogen antagonist in uterine and breast tissuesThese results are consistent with findings in clinical trialswhich suggest that EVISTA lacks estrogen-like effects on the uterus and breast tissue.

Other side effectsdrug interactionsdosageand pregnancy and breastfeeding safety information should be reviewed prior to taking this medication.

OsteoporosisEVISTA treats and prevents osteoporosis by helping make your bones stronger and less likely to breakInvasive Breast CancerIf you have osteoporosis or are at high risk for breast cancerEVISTA can be used to lower your chance of getting invasive breast cancerEVISTA will not totally get rid of your chance of getting breast cancerYour doctor can estimate your risk of breast cancer by asking you about risk factorsincludingyour agegetting olderfamily history of breast cancer in your mothersisteror daughtera history of any breast biopsyespecially an abnormal biopsy.

EVISTA is indicated for the treatment and prevention of osteoporosis in postmenopausal womensee Clinical Studies

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are pregnant, breast feeding, still have menstrual bleeds, or have had a menstrual bleed in the last year, as evista is only for postmenopausal women.

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