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Meanwhile, dostinex will help keep prolactin low , which not only makes the male have an increase in libido , but also gives him a rise in how often sex is desired.

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Following single oral doses of 0.5 mg to 1.5 mg given to 12 healthy adult volunteersmean peak plasma levels of 30 to 70 picogramspgmL of cabergoline were observed within 2 to 3 hoursOver the 0.5-to-7 mg dose rangecabergoline plasma levels appeared to be dose-proportional in 12 healthy adult volunteers and nine adult parkinsonian patientsA repeat-dose study in 12 healthy volunteers suggests that steady-state levels following a once-weekly dosing schedule are expected to be twofold to threefold higher than after a single doseThe absolute bioavailability of cabergoline is unknownA significant fraction of the administered dose undergoes a first-pass effectThe elimination half-life of cabergoline estimated from urinary data of 12 healthy subjects ranged between 63 to 69 hoursThe prolonged prolactin-lowering effect of cabergoline may be related to its slow elimination and long half-life.

Uncontrolled hypertension or known hypersensitivity to ergot derivativesHistory of pulmonarypericardialcardiac valvularor retroperitoneal fibrotic disordersSee PRECAUTIONSFibrosis

In ratsdoses higher than 0.003 mg/kg/dayapproximately 1/28 the maximum recommended human dosefrom 6 days before parturition and throughout the lactation period inhibited growth and caused death of offspring due to decreased milk secretion.

After a normal serum prolactin level has been maintained for 6 monthsDOSTINEX may be discontinuedwith periodic monitoring of the serum prolactin level to determine whether or when treatment with DOSTINEX should be reinstitutedThe durability of efficacy beyond 24 months of therapy with DOSTINEX has not been established.

Recall for product correctionbottles supplied without child-resistant caps.

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