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The dose of danazol did not influence haematological parameters.

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Danazol may cause liver damage with abdominal bleeding in people who take danazol for a long timeTell your doctor if you have or have ever had liver diseaseIf you experience any of the following symptoms call your doctor immediatelyyellowing of the skin or eyespain in stomach areaextreme tirednessor unusual bleeding or bruising.

StatinsThe risk of myopathy and rhabdomyolysis is increased by concomitant administration of danazol with statins metabolised by CYP3A 4 such as simvastatinatorvastatin and lovastatin.

Your medication needs may change if you become illhave a fever or infectionor if you have surgery or a medical emergencyTell your doctor about any such situation that affects youDo not change your medication dose or schedule without your doctor’s advice.

Acneweight gainincreased appetiteseborrhoeahirsutismhair lossvoice changewhich may take the form of hoarsenesssore throat or of instability or deepening of pitchHypertrophy of the clitorisfluid retention.

Danazol has the theoretical potential for androgenic effects in breast-fed infants and therefore either Danazol therapy or breastfeeding should be discontinued.

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