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Patients should be cautioned about the risk of bleeding associated with the concomitant use of Celexa and NSAIDsaspirinor other drugs that affect coagulation.

Coadministration of Celexa40 mg/day for 10 daysand lithium30 mmol/day for 5 dayshad no significant effect on the pharmacokinetics of citalopram or lithiumNeverthelessplasma lithium levels should be monitored with appropriate adjustment to the lithium dose in accordance with standard clinical practiceBecause lithium may enhance the serotonergic effects of citalopramcaution should be exercised when Celexa and lithium are coadministered.

Central And Peripheral Nervous System DisordersFrequentparesthesiamigraineInfrequenthyperkinesiavertigohypertoniaextrapyramidal disorderleg crampsinvoluntary muscle contractionshypokinesianeuralgiadystoniaabnormal gaithypesthesiaataxiaRareabnormal coordinationhyperesthesiaptosisstupor.

Initial dose20 mg orally once a day Maintenance dose20 to 40 mg orally once a day Maximum dose40 mg orally per day.

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