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Patients should be made aware that bupropion hydrochloride extended-release tablets xl contain the same active ingredient found in zyban , used as an aid to smoking cessation treatment, and that bupropion hydrochloride extended-release tablets xl should not be used in combination with zyban , or any other medications that contain bupropion, such as wellbutrin sr bupropion hydrochloride extended-release tablets sr , the sustained-release formulation, or wellbutrin bupropion hydrochloride tablets , the immediate-release formulation.

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Depressed mood may be a symptom of nicotine withdrawalDepressionrarely including suicidal ideation and behaviourincluding suicide attempthas been reported in patients undergoing a smoking cessation attemptThese symptoms have also been reported during Zyban treatmentand generally occurred early during the treatment course.

Patients should be treated for 7-9 weeksIf at seven weeks no effect is seentreatment should be discontinued.

Do not crush or chew this medicationDoing so can release all of the drug at onceincreasing the risk of side effectsincluding seizuresAlsodo not split the tablets unless they have a score line and your doctor or pharmacist tells you to do soSwallow the whole or split tablet without crushing or chewing.

Concomitant use of Zyban and monoamine oxidase inhibitorsMAOIsis contraindicatedAt least 14 days should elapse between discontinuation of irreversible MAOIs and initiation of treatment with ZybanFor reversible MAOIsa 24 hour period is sufficient.

Tell your doctor right away if any of these rare but very serious side effects occurmuscle pain/tenderness/weakness.

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if you tell the person giving you the drug screening test that you are taking zyban, they can do a more specific drug screening test that should not have this problem.

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