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One tablet of Ginette-35 Birth Control Pill is to be taken dailyThe tablets must be taken at about the same time every daywith some liquid as neededTablet taking should be continuousOne tablet of Ginette-35 is to be taken daily for 21 consecutive daysWithdrawal bleeding should usually occur on day 2 to 3 after the last tablet is takenEach subsequent pack is started after a 7 day tablet free intervalHow to start Ginette-35 TabletsTablet taking has to start on day 1 of the woman’s natural cyclei.ethe first day of her menstrual bleedingStarting on day 25 of the menstrual cycle is permittedbut during the first cycle a barrier method is recommended in addition for the first 7 days of tablet-takingWhen you have taken all 21 tablets in this packwait 7 days and then start a new pack of Ginette-35During the 7 days that you are not taking any tabletsyou should have your periodusually 2-4 days after you have taken your last tabletThe first tablet in every subsequent pack will always be taken on the same day of the week that you first began taking Ginette-35 tablets regardless of whether your bleeding has already ceasedwhich it usually hasor is still continuing.
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Following oral administrationCPA is completely absorbed in a wide dose rangeThe ingestion of CPA+EE attains a maximum serum level of 15 ng CPAml at 1.6 hoursThereafterdrug serum levels decrease in two disposition phases characterized by half-lives of 0.8 hours and 2.3 daysThe total clearance of CPA from serum was determined to be 3.6 ml/min/kgCPA is metabolized by various pathwaysincluding hydroxylations and conjugationsThe main metabolite in human plasma is the 15 beta-hydroxy derivative.
EE is highly but non-specifically bound to serum albumin2of the drug levels are present unboundDuring absorption and first liver passageEE is metabolized resulting in a reduced absolute and variable oral bioavailabilityUnchanged drug is not excretedEE metabolites are excreted at a urinary to biliary ratio of 4:6with a half-life of about 1 day.
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